No Effect of Multivitamins on Cognition

aking a daily multivitamin was not associated with cognitive benefits over a 12-year treatment period in male doctors aged 65 years or older in the large-scale Physicians' Health Study II (PHS II).
The study, published online December 17 in Annals of Internal Medicine, was conducted by a group led by Francine Grodstein, ScD, Brigham and Women's Hospital, Boston, Massachusetts.
"These data do not provide support for use of multivitamin supplements in the prevention of cognitive decline," the authors conclude. But they add that it is important to consider other health effects of multivitamin supplementation, including modest protection against overall cancer risk in the PHS II with long-term use.